The labs are on an island so you cant drive (completely)! There are several ways to get here, Seattle transit offers shuttle buses from the airport (SeaTac) to the Annacortes Ferry Terminal. From there you can hitch a ride on the Ferry that will take you to downtown Friday Harbor. Once you arrive it is about a half mile from the harbor to the labs.
There are several smaller airline companies that also take passengers directly from SeaTac to Friday Harbor. click the link below to find out more about the various transit options.
Additional Travel Information
You can also rent a car at SeaTac and drive to the ferry terminal. Be aware that this method requires you to make ferry reservations in advanced. Click the link below to learn more about the ferry reservations and schedules.
WSDOT Ferry Information